ABSTRACT
To gain insights on the diverse practice patterns and treatment pathways for prostate cancer (PC) in India, the Urological Cancer Foundation convened the first Indian survey to discuss all aspects of PC, with the objective of guiding clinicians on optimizing management in PC. A modified Delphi method was used, wherein a multidisciplinary panel of oncologists treating PC across India developed a questionnaire related to screening, diagnosis and management of early, locally advanced and metastatic PC and participated in a web朾ased survey (WBS) (n = 62). An expert committee meeting (CM) (n = 48, subset from WBS) reviewed the ambiguous questions for better comprehension and reanalyzed the evidence to establish a revote for specific questions. The threshold for strong agreement and agreement was ?90% and ?75% agreement, respectively. Sixty?two questions were answered in the WBS; in the CM 31 questions were revoted and 4 questions were added. The panelists selected answers based on their best opinion and closest to their practice strategy, not considering financial constraints and access challenges. Of the 66 questions, strong agreement was reached for 17 questions and agreement was achieved for 22 questions. There were heterogeneous responses for 27 questions indicative of variegated management approaches. This is one of the first Indian survey, documenting the diverse clinical practice patterns in the management of PC in India. It aims to provide guidance in the face of technological advances, resource constraints and sparse high?level evidence.
ABSTRACT
Rosai-Dorfman disease, previously known as sinus histiocytosis with massive lymphadenopathy (SHML) is one of the rare benign idiopathic proliferative diseases of phagocytic histiocytes. Majority of the patients present with painless massive cervical lymphadenopathy but intrathoracic involvement is rarely reported. Here, we report the case of a 57-year-old male with a history of chest pain, shortness of breath and generalized weakness of two-month duration. The diagnosis was formed by core biopsy of the axillary lymph node with typical emperipolesis and Immunohistochemistry markers
ABSTRACT
Primary breast lymphoma is one of the rare tumors that commonly presents as a lump with <0.5% incidence rate. It may be misdiagnosed as poorly differentiated carcinoma on routine fine-needle aspiration cytology. With appropriate treatment, this breast malignancy has a relatively better prognosis. Here, we report the case of a mammary T-cell rich B-cell non-Hodgkin lymphoma in a pre-menopausal woman diagnosed by biopsy and later confirmed by immunohistochemistry.